WebFeb 8, 2024 · Chemotherapy- induced peripheral neuropathy (CIPN) is one of the major dose-limiting side effects of many chemotherapeutic agents including platinum analogues, vinca alkaloids, and taxanes [].The structure and function of peripheral motor, sensory and autonomic neurons are affected, causing peripheral neuropathic signs and symptoms … WebDec 1, 2014 · Abstract. Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling pain condition resulting from chemotherapy for cancer. Severe acute CIPN may …
Chemotherapy-induced peripheral neuropathy (CIPN): current therapie…
WebJan 21, 2015 · The review provided evidence that acupuncture may be useful in improving symptoms and pain for patients experiencing CIPN, but this evidence is considered to be limited. Larger, randomized, controlled … WebMay 31, 2024 · This review focusses on the commonly used antineoplastic substances oxaliplatin, cisplatin, vincristine, docetaxel, and paclitaxel which interfere with the cancer cell cycle—leading to cell death and tumor degradation—and cause severe acute and chronic peripheral neuropathies. daydreaming and consciousness
Animal models of chemotherapy-induced peripheral neuropathy: …
WebJan 5, 2024 · Chemotherapy-induced peripheral neuropathy (CIPN), a severe dose-dependent toxicity, often results in chemotherapy dose reduction or cessation, adversely affecting efficacy of chemotherapy itself. The resulting neurotoxicity profoundly impacts the quality of life of survivors. WebSep 10, 2024 · Two systematic reviews of existing CIPN assessment tools (Griffith et al. 2010 , Haryani et al. 2024 ) both recommended the GOG-Ntx and the TNS, which are widely used worldwide. The advantage of the TNS is that it combines subjective assessment by the patient with objective assessment by a medical professional. However, it is more … WebSep 3, 2024 · Chemotherapy-induced peripheral neuropathy (CIPN) is a major adverse effect of various chemotherapeutic drugs for cancer. 1 Platinum agents, especially cisplatin, are an important group of chemotherapeutic drugs. They are used in the management of various cancers with curative and/or palliative intent. daydreaming and dissociation