WebDec 28, 2024 · Objective: This study is aimed at exploring the molecular mechanism of Shufeiya recipe in the treatment of pulmonary hypertension (PH) using network pharmacology and molecular docking analysis. Methods: Active components and their … Objective. This study is aimed at exploring the molecular mechanism of Shufeiya recipe in the treatment of pulmonary hypertension (PH) using network pharmacology and molecular docking analysis. Methods. Active components and their target proteins in the recipe were screened using the TCMSP … See more Pulmonary hypertension (PH) is a chronic progressive pulmonary vascular system disease caused by pulmonary arteriole obstruction, and it is characterized by pulmonary artery … See more A total of 67 active components of Shufeiya recipe were obtained from the TCMSP database, including 3 active components from platycodi radix, 52 active components from Salvia miltiorrhiza, 10 active … See more Based on the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) (http://tcmspw.com/tcmsp.php) [ 1. J. Ru, P. Li, J. Wang et al., “TCMSP: a database of systems … See more The occurrence of PH is closely related to abnormalities in the pulmonary vascular function and/or structure. Long-term hypoxia or other factors damage the endothelial cell … See more
Shufeiya Recipe activated the PI3K/AKT/eNOS signaling pathway …
WebFeb 18, 2024 · The traditional Chinese medicine (TCM) compound "Shufeiya Recipe" was used to intervene in monocrotaline- (MCT-) induced pulmonary hypertension in rats. The rats were randomly divided into the control group, model group, positive drug (Sildenafil) … Web(a) Shufeiya Recipe significantly downregulated the level of ROS accumulation of PH rats, . (b–d) Shufeiya Recipe increased COX-1, COX-2, and Mn-SOD contents of PH rats, . ## vs. the control group; vs. the model group; and , vs. the low-dose group of Shufeiya Recipe. chinese reality television shows
Network Pharmacology and Molecular Docking Analysis of …
WebOct 3, 2024 · The risk of metabolic diseases is greatly increased by both chronic and acute stress. Irrespective of the cause, chronic or acute stress has the capacity to alter an individual’s cytokine profile. For instance, it has been observed that stress significantly increased concentrations of IL 1 beta, IL 6 and TNF alpha. Alteration in cytokine profiles … WebNetwork Pharmacology and Molecular Docking Analysis of Shufeiya Recipe in the Treatment of Pulmonary Hypertension. Biomed Res Int. 2024;2024:7864976. PubMed Abstract available. BMC Pulm Med. ELNADY MA, Elkorashy R, Nabil A, Ibrahim EK, et al Predictors of pulmonary hypertension in patients with hypersensitivity pneumonitis. Web(c–e) Different doses of Shufeiya Recipe upregulated the protein expression level of p-PI3K, p-AKT, and p-eNOS. n=3, ##P<0.01 vs. the control group; ∗P<0.05, ∗∗P<0.01 vs. the model group ... chinese rebel of 1900 clue